List of publications

[For a full list of publications on Google Scholar, click here]

  • Nguyen, L.N., Smith, B.M., Jain P.K.* Enhancement of trans-cleavage activity of Cas12a with engineered crRNA enables amplified nucleic acid detection Nature Communications, 2020. (*Corresponding author) [Manuscript in review]

Nguyen, L.N., Smith, B.M., Jain P.K.* Enhancement of trans-cleavage activity of Cas12a with engineered crRNA enables amplified nucleic acid detection BioRxiv, 2020; DOI: https://doi.org/10.1101/2020.04.13.036079. (*Corresponding author, Preprint)  [Download pdf] [View]Downing M and Jain PK*, Mesoporous silica nanoparticles: synthesis, properties, and biomedical applications. Nanoparticles for Biomedical Applications, 2019; 267-281, Book Chapter. (*Corresponding author) [View]

  • Jain PK*, Lo JH, Rananaware S, Downing M, Panda A, Tai M, Raghavan S, Fleming HE and Bhatia SN*. Non-viral delivery of CRISPR/Cas9 complex using CRISPR-GPS nanocomplexes. Nanoscale, 2019; 11, 21317-21323 (*Co-corresponding author)  [Download pdf] [View]
  • Jain PK, Ramanan V, Schepers AG, Dalvie N, Panda A, Fleming HE and Bhatia SN. Development of light-activated CRISPR using photocleavable protectors of guide RNAs. Angewandte Chemie International Edition2016; 55, 12440. [Download pdf] [View] [News articles] [Altmetrics]

  • Sarode BR, Jain PK and Friedman SH. Polymerizing Insulin with Photocleavable Linkers to Make Light-Sensitive Macropolymer Depot Materials. Macromolecular Bioscience2016; 16 (8): 1138-1146. [Download pdf] [View] [Featured on the cover]

  • Dudani JS, Jain PK, Kwong GA, Stevens KR and Bhatia SN. Photoactivated Spatiotemporally-Responsive Nanosensors of in Vivo Protease Activity. ACS Nano, 2015; 9(12), 11708-11717. [Download pdf] [View]

  • Kala A, Jain PK and Friedman SH. Patterning of cells through patterning of biology. Molecular BioSystems, 2014;10, 1689-1692. [Download pdf] [View]


  • Kala A, Jain PKKarunakaran D, Shah S and Friedman SH. The synthesis of tetra-modified RNA for the multidimensional control of gene expression via light-activated RNA interference. Nature protocols, 2014; 9(1), 11-20. [Download pdf] [View]


  • Jain PK, Shah S and Friedman SH. Patterning of gene expression using new photolabile groups applied to light activated RNAi. Journal of the American Chemical Society, 2011; 133(3), 440-446. [Download pdf] [View]

  • Shah S, Jain PK, Kala A, Karunakaran D and Friedman SH. Light-activated RNA interference using double-stranded siRNA precursors modified using a remarkable regiospecificity of diazo-based photolabile groups. Nucleic Acids Research, 2009; 37(13), 4508-4517[Download pdf] [View] [Featured on the cover]

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