Yiider Tseng » Biomolecular and Cellular Engineering for Human Health

Jang LabWe perform fundamental research and develop technologies for improving human health. Ongoing research includes studies of nanoparticle-biological interactions, cellular mechanics, engineering of proteases and CRISPR-Cas systems, development of new types of sensors, and new materials for biomedical applications.

Faculty

Photo of Yiider Tseng

Yiider Tseng

Associate Professor and MS Program Coordinator
Work Office: CHE 223 1006 Center Drive Gainesville FL 32611 Work Phone: (352) 392-0862

Biography

MY LAB FOCUSES ON COMBINING NEW ENGINEERING PRINCIPLES WITH ADVANCED LIFE SCIENCE METHODS for the purpose of developing a systematic, quantitative and integrative way to understand fundamental biological phenomena at the molecular and cellular levels. My research has implications on tissue engineering, wound repairs, microorganism invasions and disease states, such as cancer metastasis.

MY RESEARCH LABORATORY develops high-throughput/high-content methods to establish more sophisticated cell dynamic models. After identifying the key correlation among different subcellular activities, an integrative cell activity model can be established and the spatiotemporal connections between the subcellular activities can guide us to understand the comprehensive molecular mechanisms.

Education

Ph.D., 1999, Johns Hopkins University

selected Publications

  • Wu, P. H., Hung S. H., Ren, T., Shih, I. M. and Tseng, Y., Cell cycle-dependent alternation in NAC1 nuclear body dynamics and morphology, Physical Biology 8: 015005 (2010).
  • Wu, P. H., Agarwal, A, Hess, H., Khargonekar, P. P. and Tseng, Y., Analysis of video-based microscopic particle trajectories using Kalman filtering. Biophysical Journal 98: 2822-2830 (2010).
  • Wu, P. H., Nelson, N., and Tseng, Y., A general method for improving spatial resolution by optimization of electron multiplication in CCD imaging, Optical Express 18: 5199-5212 (2010).
  • Wu, P. H., Arce, S. H., Burney, P. R. and Tseng, Y., A novel approach to high accuracy of video-based microrheology, Biophysical Journal 96: 5103-5111 (2009).
  • Hess, H and Tseng, Y., Active intracellular transport of nanoparticles: opportunity or threat? ACS Nano 1: 390-392 (2007)
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Office: CHE 223 Gainesville FL 32611