Congratulations to Dr. Jon Dobson, J. Crayton Pruitt Family Professor, and Dr. Carlos Rinaldi, Chair, Department of Chemical Engineering & Dean’s Leadership Professor, for their recently published book entitled, “Nanomagnetic Actuation in Biomedicine: Basic Principles and Applications.”
The book published by CRC Press focuses on the fundamentals and applications of magnetic actuation. The manipulation and control of cells and sub-cellular structures through magnetic nanoparticle-based actuation is a relatively new technique that has led to novel and exciting biomedical applications. Nanomagnetic actuation is being used in laboratory studies of stem cells to determine how these mechanical cues can be used to control stem cell differentiation for regenerative medicine applications. This book explores this rapidly expanding field. It will interest industry bioscientists and biomedical engineers as well as academics in cellular biomechanics, cell and tissue engineering, and regenerative medicine.
Dobson’s research focuses on biomedical applications of magnetic micro- and nanoparticles. His group has developed novel technologies for 1) magnetic targeting and remote activation of cell signaling pathways for cell engineering and stem cell therapy; 2) magnetic nanoparticle-based gene transfection delivery; and 3) magnetic targeting of modified cell carriers for cancer therapy and regenerative medicine. In addition, he has also led a multi-national research program developing novel imaging and characterization techniques to quantify, characterize and map iron compounds related to neurodegenerative diseases such as Alzheimer’s and Parkinson’s.
Rinaldi’s research is focused on advancing the understanding and biomedical applications of suspensions of magnetic nanoparticles. Of particular interest are situations where the particles respond to magnetic fields by rotating, exerting forces/torques on biological structures, or dissipating the energy of the magnetic field in the form of heat. Work in Rinaldi’s lab spans theoretical and simulation investigation of magnetic nanoparticle response to magnetic fields, nanoparticle synthesis and modification, characterization of nanoparticle physical, chemical and magnetic properties, and testing the interactions of magnetic nanoparticles with cells and tissues.